Low water peak non-dispersive displacement single-mode fiber is suitable for transmission system of the full band 1280nm ~ 1625nm, which not only maintains the low dispersion of the traditional band 1310nm, but also has a low loss at 1383nm, making the E band (1360nm ~ 1460nm) fully utilized. The loss and dispersion of the whole band from 1260nm to 1625nm are optimized, and the bending loss of 1625nm wavelength is reduced, which provides bandwidth resources for backbone network, MAN and access network.